Gentamicin sulfate CAS NO：1405-41-0

Wide Range of Antibacterial Properties

This substance exhibits potent bactericidal effects against various Gram-negative strains, such as Escherichia coli, Shigella bacteria and Pseudomonas aeruginosa.

Multiple Clinical Treatment Scenarios

It can be adopted to remedy systemic illnesses, focal lesions, eye infections and intestinal disorders. Besides, it also acts as a preoperative preventive drug before colorectal operations.

Potent Synergistic Effect in Combined Medication

When administered alongside metronidazole or clindamycin, this agent can strengthen the preventive effect against postoperative bacterial infections.

Stable Chemical Property and Reliable Curative Effect

Its chemical composition stays intact within water solutions stored at 37°C for as long as five days, which guarantees steady and stable therapeutic effects during application.

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Product Details

Gentamicin sulfate falls under the category of aminoglycoside bactericidal antibiotics, whose molecular framework is constructed from aminosugar and aglycone moieties. Being the sulfate salt form of gentamicin, it shares a similar antibacterial coverage with kanamycin.

This pharmaceutical compound mainly targets both systemic and regional infectious diseases triggered by Gram-negative pathogenic bacteria, including Escherichia coli, Shigella dysenteriae, Klebsiella pneumoniae, Proteus spp. and Pseudomonas aeruginosa. Within ophthalmic treatment, it is widely prescribed to address ocular ailments such as conjunctivitis and keratitis.

Gentamicin sulfate CAS NO：1405-41-0

Parameters

Melting point	218-237°C
alpha	D25 +102°
density	1.000 g/cm3
storage temp.	2-8°C
solubility	H2O: 50 mg/mL As stock solution, store at −20°C. Stable at 37°C for 5 days.
form	powder
color	colorless to light yellow
Odor	odorless
PH	4.0-5.5 (0.1g/mL in H2O)
optical activity	[α]20/D +110±8°, c = 1% in H2O
biological source	Micromonospora purpurea
Water Solubility	Soluble in water
Merck	134403
InChIKey	RDEIXVOBVLKYNT-HDZPSJEVSA-N
CAS DataBase Reference	1405-41-0(CAS DataBase Reference)
EPA Substance Registry System	Gentamicin sulfate (1405-41-0)
Safety Information
Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	23-36/37-45-22-24/25
WGK Germany	2
RTECS	LY2625000
F	3
HS Code	29419010
Toxicity	LD50 in mice (mg base/kg): 430 i.p.; 485 s.c.; 75 i.v.; >9050 orally (Black)

Gentamicin sulfate CAS NO：1405-41-0

Oral administration of this antibacterial agent is available for intestinal infectious disorders and preoperative intestinal disinfection prior to colorectal operations. Moreover, pairing it with metronidazole or clindamycin can effectively cut down the risk of infectious complications after colon surgery.

Gentamicin sulfate CAS NO：1405-41-0