Dexamethasone CAS:50-02-2

Robust Anti-Inflammatory Efficacy

As a potent glucocorticoid, dexamethasone blocks the release of pro-inflammatory factors to relieve clinical manifestations caused by diverse inflammatory pathologies.

Combination Regimen Advantages

Clinicians often pair it with other therapeutic substances to generate synergistic therapeutic outcomes, supporting comprehensive and optimized disease management.

Multi-Scenario Clinical Utilization

Possessing anti-allergy and anti-endotoxin properties, the drug finds extensive clinical use for hypersensitivity disorders, autoimmune ailments and shock rescue.

Palliative Therapeutic Value

While it cannot eliminate fundamental lesions, its immune-regulating and inflammation-suppressing effects effectively restrain pathological development, making it vital for symptomatic intervention in a wide range of illnesses.


Product Details
As an essential clinical glucocorticoid, dexamethasone is commonly matched with other drugs to maximize treatment results. It suppresses the production of inflammatory substances to realize powerful anti-inflammatory, anti-allergy and antitoxic activity via immune regulation.
It works well for mitigating clinical symptoms but does not offer radical treatment, only reducing pathological symptoms without tackling the source of diseases. Joint administration with other pharmaceuticals is necessary to realize all-round disease control. This combined treatment mode optimizes curative effects and stabilizes inflammatory status for numerous clinical ailments.


Dexamethasone CAS:50-02-2


Parameters

Melting point 

262-264 °C (lit.)

alpha 

75 º (c=1, dioxane)

Boiling point 

568.2±50.0 °C(Predicted)

density 

1.1283 (estimate)

refractive index 

76 ° (C=1, Dioxane)

Fp 

9℃

storage temp. 

2-8°C

solubility 

ethanol: 1 mg/mL

form 

powder

pka

12.13±0.70(Predicted)

color 

off-white

biological source

synthetic (organic)

Water Solubility 

10 mg/100 mL (25 ºC)

Sensitive 

Light Sensitive

Merck 

142943

BRN 

2066651

BCS Class

1 (CLogP), 3 (LogP)

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.

InChIKey

UREBDLICKHMUKA-CXSFZGCWSA-N

CAS DataBase Reference

50-02-2(CAS DataBase Reference)

NIST Chemistry Reference

Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2)

EPA Substance Registry System

Dexamethasone (50-02-2)

 

Safety Information

Hazard Codes 

Xi,Xn,T,F

Risk Statements 

43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11

Safety Statements 

36/37-45-36-26-22-16

RIDADR 

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany 

2

RTECS 

TU3980000

TSCA 

Yes

HS Code 

29372210

Hazardous Substances Data

50-02-2(Hazardous Substances Data)

Toxicity

LD50 oral in rat: > 3gm/kg


Dexamethasone CAS:50-02-2


Dexamethasone CAS:50-02-2


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