Doxycycline hydrochloride CAS:10592-13-9

Wide Antimicrobial Coverage

The active ingredient suppresses the growth of both Gram-positive and Gram-negative bacteria, even strains that show resistance against conventional tetracyclines.

Strong Antibacterial Effect

Compared with tetracycline, its bacteriostatic capacity is around 10-fold stronger, offering better curative performance.

Diverse Therapeutic Uses

It is widely applied to treat multiple infectious conditions such as respiratory and urinary tract infections, typhoid and mycoplasma pneumonia.

Ideal Solubility Performance

High solubility in water facilitates efficient absorption and guarantees satisfactory bioavailability after administration.


Product Details

Doxycycline HCl appears as pale blue or yellow crystal powder without any odor, featuring a unique bitter taste and obvious moisture absorption property. The material possesses great dissolubility in water and methanol, but barely dissolves in ethanol and acetone.


Doxycycline hydrochloride CAS:10592-13-9


The ingredient delivers broad antimicrobial coverage, inhibiting Gram-positive cocci and Gram-negative bacilli alike. It boasts roughly tenfold stronger antibacterial effects than tetracycline and remains effective against tetracycline-tolerant bacteria. It is widely used clinically for respiratory infections, chronic bronchitis, pneumonia, urinary tract disorders, skin macules, typhoid fever and mycoplasma pneumonia. (CAS Registry Number: 24390-14-5)


Doxycycline hydrochloride CAS:10592-13-9


Parameters

Melting point 

195-201℃

Fp 

87℃

storage temp. 

Inert atmosphere,2-8°C

solubility 

H2O: 50 mg/mL, clear, yellow-green

form 

powder

color 

yellow

biological source

synthetic

Water Solubility 

Soluble in water.

BCS Class

1

InChIKey

RUYHIJHUVHIMIR-PGTYNCOMNA-N

SMILES

O[C@@]12C(C(C(=O)N)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]([C@]1([H])[C@H](C3C=CC=C(O)C=3C(=O)C1=C2O)C)O)=O.Cl |&1:1,9,13,15,16,18,r|

CAS DataBase Reference

10592-13-9(CAS DataBase Reference)

 

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38

Safety Statements 

26-36/37

RIDADR 

NA 1993 / PGIII

WGK Germany 

3

8

HS Code 

29413000


Doxycycline hydrochloride CAS:10592-13-9

 



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