L-Carnosine CAS：305-84-0
Diverse Bioactive Profiles
Powerful Metal Ion Complexation
Comprehensive Physiological Advantages
Robust Antioxidative Effects
β-alanyl-L-histidine, referred to as L-Carnosine (CAS: 305-84-0), is an in-vivo dipeptide synthesized from β-alanine and L-histidine. It can be isolated from multiple rat tissues covering olfactory bulb, striated muscle, brain, kidney and spleen, and it naturally accumulates in human skeletal muscle as well. Exhibiting diversified biological properties, L-Carnosine serves as an efficient metal ion binder, which can combine firmly with copper, cobalt, nickel, cadmium and zinc to form stable chelates.
L-Carnosine
The material covers abundant application scenarios in different industries. Researchers apply it to pharmaceutical projects targeting neuroprotection and cardiovascular health improvement. It is a mainstream antioxidant and anti-aging raw material for oral nutritional supplements. Food processing employs it as a functional auxiliary additive. Skincare cosmetics add this ingredient to delay skin aging symptoms. Meanwhile, plenty of academic researches keep exploring its internal physiological action pathways.
Safety Information
Melting point | 253 °C (dec.) (lit.) |
alpha | 20.9 º (c=1.5, H2O) |
Boiling point | 367.84°C (rough estimate) |
density | 1.2673 (rough estimate) |
vapor pressure | 0Pa at 25℃ |
refractive index | 21 ° (C=2, H2O) |
storage temp. | -20°C |
solubility | DMSO (Very Slightly), Water (Slightly) |
pka | 2.62(at 25℃) |
form | crystalline |
color | White |
Odor | at 100.00?%. odorless |
Optical Rotation | +24.120 |
Water Solubility | almost transparency |
Merck | 14,1850 |
BRN | 87671 |
Stability: | Stable, but may be heat sensitive - store cold. Incompatible with strong oxidizing agents. |
InChIKey | CQOVPNPJLQNMDC-ZETCQYMHSA-N |
LogP | -3.8 at 22℃ |
CAS DataBase Reference | 305-84-0(CAS DataBase Reference) |
EPA Substance Registry System | L-Histidine, .beta.-alanyl- (305-84-0) |
Safety Information
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 24/25-36-26 |
WGK Germany | 2 |
RTECS | MS3080000 |
F | 3-10 |
TSCA | Yes |
HS Code | 29332900 |
Toxicity | LD50 oral in mouse: > 14930mg/kg |
