Acetylsalicylic acid CAS:50-78-2

Pain Relief & Anti-Inflammatory Activity

Aspirin belongs to non-steroidal anti-inflammatory compounds with proven pain-killing and anti-inflammatory potency, and it is extensively utilized in clinical practice for related symptoms.

Mechanism Against Thrombosis

By permanently inhibiting cyclooxygenase, aspirin limits platelet clumping. This characteristic prevents blood clots and provides reliable anti-thrombotic benefits.

Cardiac and Cerebrovascular Care

Regular aspirin intake markedly decreases fatal risks from acute heart attacks and cerebral vascular disorders, helping preserve cardiovascular wellness.

Anti-Tumor Preventive Value

Latest research findings reveal aspirin can reduce the occurrence rate of colon and rectal cancers, extending its application range beyond standard medical treatments.

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Product Details

Acetylsalicylic acid, commonly named aspirin, falls under the category of nonsteroidal anti-inflammatory drugs (NSAIDs). Its initial development aimed to relieve pain and suppress inflammatory reactions. Later research found that the substance permanently blocks cyclooxygenase, preventing platelets from clumping together and delivering anti-clotting benefits. Ongoing medical exploration has identified more valuable pharmacological uses for this drug. It effectively reduces death risks from heart attacks and strokes, and relevant evidence proves it can decrease the probability of colorectal cancer development. Such advantages extend its clinical uses far beyond its original treatment purposes.

Acetylsalicylic acid CAS:50-78-2

Melting point	134-136 °C (lit.)
Boiling point	272.96°C (rough estimate)
density	1.35
refractive index	1.4500 (estimate)
Fp	250 °C
storage temp.	2-8°C
solubility	H2O: 10 mg/mL at 37 °C
form	crystalline
color	white
pka	3.5(at 25℃)
biological source	synthetic
Water Solubility	3.3 g/L (20 ºC)
ε(extinction coefficient)	190 at 298nm in aqueous base at 1mM
	409 at 231nm in aqueous base at 1mM
	466 at 230nm in aqueous acid at 1mM
	68 at 278nm in aqueous acid at 1mM
Merck	14851
BRN	779271
Exposure limits	ACGIH: TWA 5 mg/m3
Exposure limits	NIOSH: TWA 5 mg/m3
BCS Class	3
Stability:	Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.
InChIKey	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
LogP	1.19
CAS DataBase Reference	50-78-2(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 2-(acetyloxy)-(50-78-2)
EPA Substance Registry System	Aspirin (50-78-2)
Safety Information
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26-36/37/39
OEB	B
OEL	TWA: 5 mg/m3
RIDADR	UN 1851
WGK Germany	1
RTECS	VO0700000
TSCA	Yes
HazardClass	6.1
PackingGroup	III
HS Code	29182210
Hazardous Substances Data	50-78-2(Hazardous Substances Data)
Toxicity	LD50 orally in mice, rats: 1.1, 1.5 g/kg (Hart)