Idebenone CAS#58186-27-9
Powerful Antioxidant Activity: It can penetrate cell membrane and blood-brain barrier effectively, scavenge intracellular free radicals, relieve oxidative damage to nerve cells and skin cells.
Neuroprotective & Metabolic Promotion Effect: Improve cerebral mitochondrial energy metabolism, boost glucose and oxygen utilization in brain tissue, alleviate symptoms caused by cerebral hypoxia and insufficient blood supply.
Stable Liposoluble Property: Excellent fat solubility, easy to be absorbed by skin and nerve tissue, compatible with cosmetic oil phases and pharmaceutical excipients without stratification.
Multi-scenario Application Value: Dual application in pharmaceutical treatment and high-end skincare, mild irritation, long-lasting antioxidant efficacy with stable formulation performance.
Idebenone is a synthetic coenzyme Q10 analog, a lipophilic benzoquinone derivative with outstanding anti-oxidation and neuroprotection functions, widely used in brain disease medicine and anti-aging cosmetic raw materials.
Chemical & Physical Properties
| Property | Value |
|---|---|
| Melting point | 52–55 °C |
| Density | 1.24 g/cm³ |
| Storage temp | 2–8°C sealed dark warehouse, avoid light and high temperature |
| Solubility | Insoluble in water, soluble in ethanol, vegetable oil and organic solvents |
| Form | Orange-yellow crystalline powder |
| Color | Orange yellow |
| Odor | Slight characteristic odor |
| PH Value | Neutral (oil solution) |
| Hygroscopicity | Slightly hygroscopic, sensitive to strong light |
| Stability | Stable under sealed dark storage, easy to degrade under UV irradiation |
| EINECS No. | 261-153-0 |
| CAS DataBase Reference | 58186-27-9 |
Safety Information
| Item | Value |
|---|---|
| Hazard Codes | Xi |
| Risk Statements | R36/38 |
| Safety Statements | S26, S36 |
| F | Non-flammable |
| TSCA | Yes |
| HS Code | 2914690090 |
Main applications:
Pharmaceutical field: Treatment drug for cerebral infarction sequelae, cerebral arteriosclerosis, improves mental and cognitive disorders.
Cosmetic field: High-end anti-aging raw material, reduce fine lines, fade pigmentation, repair damaged skin barrier, anti-photoaging.






