Calcium D-Pantothenate
Calcium Pantothenate: A naturally occurring form of pantothenic acid (vitamin B5) that serves as an essential nutrient for maintaining metabolic functions and overall wellbeing.
Regulatory Status: Designated as Generally Recognized as Safe (GRAS) in both the United States and European Union, confirming its safety profile for food and supplement applications.
Nutritional Standards: Complies with US FDA regulations requiring inclusion in infant formula at 300 mcg per 100 calories, demonstrating its critical role in early development.
Application Range: Commonly utilized in dietary supplements, functional foods, and fortified nutritional products to support health maintenance across various life stages.
Calcium pantothenate, chemically known as calcium D-pantothenate, represents the calcium salt of pantothenic acid (vitamin B5) - an essential nutrient naturally present in various food sources. This compound holds Generally Recognized as Safe (GRAS) status in both the United States and European Union. In accordance with FDA guidelines, prepared infant formula must contain a minimum of 300 micrograms per 100 calories of this essential vitamin.
This compound finds application in biochemical research as a nutritional component in tissue culture media. Therapeutically, it is utilized in managing pantothenic acid deficiency, peripheral neuritis, and postoperative intestinal spasms.
As a food fortificant, calcium pantothenate is incorporated into infant formulas at concentrations of 15-28 mg/kg, while beverage applications typically utilize 2-4 mg/kg for nutritional enhancement.
Calcium D-Pantothenate Chemical Properties
Melting point | 190 °C |
Alpha | 26.5 º (c=5, in water) |
Refractive index | 27 ° (C=5, H2O) |
Fp | 145 °C |
Storage temp | 2-8°C |
Solubility | H2O: 50 mg/mL at 25 °C, clear, nearly colorless |
Form | |
Color | White or almost white |
PH | 6.8-7.2 (25℃, 50mg/mL in H2O) |
Odor | Odorless |
Biological source | synthetic (organic) |
Optical Rotation | [α]20/D +27±2°, c = 5% in H2O |
Water Solubility | Soluble in water |
Sensitive | Hygroscopic |
Merck | 14,7015 |
BRN | 3769272 |
Stability | Stable, but may be moisture or air sensitive. Incompatible with strong acids, strong bases. |
InChIKey | FAPWYRCQGJNNSJ-UBKPKTQASA-L |
LogP | -0.849 (est) |
CAS DataBase Reference | 137-08-6(CAS DataBase Reference) |
EPA Substance Registry System | Calcium pantothenate (137-08-6) |
Safety Information
Hazard Codes | Xn |
Risk Statements | 20/21/22-37/38-41-48 |
Safety Statements | 24/25-45-36/37/39-26-22 |
WGK Germany | 1 |
RTECS | RU4375000 |
F | 3-10 |
TSCA | Yes |
HS Code | 29362400 |
