Methylparaben
Antibacterial Efficacy: Nephestyl acetate demonstrates high effectiveness against fungal and yeast microorganisms, positioning it as a strong preservative option for cosmetic products.
Application in Cosmetics: Originally known for food preservation, it has been increasingly adopted and developed as a reliable preservative in the cosmetics industry.
Chemical Stability: The compound remains stable under standard environmental conditions but is incompatible with strong oxidizing agents and bases.
Solubility Profile: It is soluble in ethanol, which facilitates its smooth integration into a variety of cosmetic formulations.
Methylparaben was initially used as a preservative in food products. Through subsequent research and development, it has been adapted for use in the cosmetics industry, where it serves as an efficient preservative agent. Recognized for its strong antibacterial qualities, it exhibits notable efficacy against molds and yeasts, establishing it as a valuable component in numerous cosmetic formulations.
That said, its performance is relatively limited against certain bacterial groups—such as Gram-negative bacteria and lactic acid bacteria. Therefore, it is frequently used in combination with other preservatives to broaden its antimicrobial spectrum and improve its effectiveness in cosmetic applications.
Parameters
Melting point | 125-128 °C (lit.) |
Boiling point | 298.6 °C |
density | 1,46g/cm |
vapor pressure | 0.000005 hPa (20 °C) |
FEMA | 2710 | METHYL P-HYDROXYBENZOATE |
refractive index | 1.4447 (estimate) |
Fp | 280°C |
storage temp | room temp |
solubility | ethanol: soluble0.1M, clear, colorless |
pka | pKa 8.15(H2O,t =20.0) (Uncertain) |
form | Crystalline Powder |
color | White to almost white |
Odor | odorless or faint char. odor, sl. burning taste |
PH | 5.8 (H2O, 20°C) (saturated solution) |
biological source | synthetic |
Water Solubility | Slightly soluble in water. |
FreezingPoint | 131℃ |
Merck | 14,6107 |
BRN | 509801 |
Stability | Stable. Incompatible with strong oxidizing agents, strong bases. |
InChIKey | LXCFILQKKLGQFO-UHFFFAOYSA-N |
LogP | 1.98 at 20℃ |
CAS DataBase Reference | 99-76-3(CAS DataBase Reference) |
NIST Chemistry Reference | Benzoic acid, 4-hydroxy-, methyl ester(99-76-3) |
EPA Substance Registry System | Methylparaben (99-76-3) |
Safety Information
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-20/21/22-36 |
Safety Statements | 26-36-24/25-39 |
RIDADR | UN 2769 |
WGK Germany | 1 |
RTECS | DH2450000 |
Autoignition Temperature | >600 °C |
TSCA | Yes |
HS Code | 29182930 |
Hazardous Substances Data | 99-76-3(Hazardous Substances Data) |
