2-Methyl-4-isothiazolin-3-one
Broad-Spectrum Antimicrobial Efficacy: Demonstrates strong inhibitory activity against a wide variety of microorganisms, such as bacteria, fungi, and yeasts.
Rapid Antimicrobial Action: Acts quickly and potently by disrupting microbial metabolic processes and effectively controlling their proliferation.
Biofilm Formation Prevention: Helps prevent the development of biofilms, increasing its utility in preservation, sterilization, and disinfection applications.
High Water Solubility: Exhibits excellent solubility in water (489 g/L at 20 °C), facilitating its use across a diverse range of industrial and aqueous formulations.
Methylisothiazolinone (MIT) is a synthetic biocide that entered the Chinese market in recent years, having been initially developed and adopted in Europe. As a member of the isothiazolinone family, it acts as a highly efficient antimicrobial agent capable of suppressing a broad spectrum of microorganisms—such as bacteria, fungi, and yeast—by disrupting critical cellular processes. This class of compounds is particularly distinguished by its rapid mechanism of action, impairing metabolic functions and inhibiting proliferation of microbes while also preventing biofilm formation. These attributes contribute to its growing preference in industrial and commercial settings, especially in applications requiring effective preservation and disinfection.
Parameters
Melting point | 254-256 °C(lit.) |
Boiling point | bp0.03 93° |
density | 1.25 (14% aq.) |
vapor pressure | <0.1 mm Hg ( 25 °C) |
storage temp. | 2-8°C |
solubility | Chloroform, Ethyl Acetate |
form | Solid |
pka | -2.03±0.20(Predicted) |
color | Yellow |
Water Solubility | 489g/L at 20℃ |
BRN | 606203 |
InChIKey | BEGLCMHJXHIJLR-UHFFFAOYSA-N |
LogP | -0.486 at 20℃ |
CAS DataBase Reference | 2682-20-4(CAS DataBase Reference) |
NIST Chemistry Reference | 3(2H)-isothiazolone, 2-methyl-(2682-20-4) |
EPA Substance Registry System | 2-Methyl-3(2H)-isothiazolone (2682-20-4) |
Safety Information
Hazard Codes | N,C,T |
Risk Statements | 50/53-50-43-34-20/21/22-37-23-22 |
Safety Statements | 60-61-36/37/39-26-24-45 |
RIDADR | UN 3077 9/PG 3 |
WGK Germany | 2 |
RTECS | FE1250000 |
HazardClass | 8 |
PackingGroup | III |
HS Code | 29349990 |
Hazardous Substances Data | 2682-20-4(Hazardous Substances Data) |
