Cocamidopropyl Betaine, CAS#61789-40-0
Appearance: It is a clear to pale yellow viscous liquid, with mild characteristic odor, low irritation and good compatibility with various surfactants.
Solubility: Freely soluble in water, soluble in aqueous alcohol solutions; insoluble in mineral oil and vegetable oil.
Stability & pH Performance: The pH value of its aqueous solution (10% active substance) is 5.0–7.0. It remains stable over a wide pH range, and maintains good performance in weak acid and weak alkaline environments. It is stable under normal storage conditions.
Basic Function Features: It is an amphoteric surfactant derived from coconut fatty acid. It has excellent foaming, foam stabilizing, wetting and detergency properties. It can reduce the irritation of anionic surfactants and is widely used in mild personal care formulations.
Cocamidopropyl betaine, characterized by the molecular formula C₁₉H₃₈N₂O₃, presents as a clear to pale yellow viscous liquid. It is readily soluble in water and water-alcohol mixtures, and immiscible with oils. Its 10% active solution pH ranges from 5.0 to 7.0, and it exhibits stable performance across weakly acidic to weakly alkaline conditions. The substance is a mild amphoteric surfactant, compatible with anionic, cationic and nonionic surfactants, and is famous for low skin and eye irritation. It is commonly used as foaming agent, foam booster and viscosity regulator in daily chemical products.
| Chemical Properties | Parameter |
|---|---|
| CAS No. | 61789-40-0 |
| Molecular Formula | C₁₉H₃₈N₂O₃ |
| Molecular Weight | 342.52 g/mol |
| Active Content | 30–35 wt% |
| pH (10% active solution, 20℃) | 5.0–7.0 |
| Solubility | Soluble in water, aqueous ethanol; insoluble in oils |
| Appearance | Clear to pale yellow viscous liquid |
| Odor | Mild, faint coconut odor |
| Storage Temp | Store between 5–30 ℃ |
| Stability | Stable under normal conditions; avoid strong oxidizing agents and strong acids |
| Refractive Index | 1.370–1.390 |
| Viscosity | 1000–5000 mPa·s (25℃) |
| InChIKey | ZZJIAOJZVDQOLG-UHFFFAOYSA-N |
| NIST Chemistry Reference | Cocamidopropyl betaine (61789-40-0) |
| EPA Substance Registry System | Ammonium, (3-cocoamidopropyl)dimethylcarboxymethyl-, hydroxide, inner salt |
| Safety Information | Details |
|---|---|
| GHS Classification | Warning |
| Hazard Statements | H315: Causes skin irritation; H319: Causes serious eye irritation |
| Precautionary Statements | P264, P280, P302+P352, P305+P351+P338 |
| Risk Statements | R36/38 |
| Safety Statements | S26, S36 |
| WGK Germany | 1 |
| RTECS | Not available |
| Grade | Cosmetic Grade / Industrial Grade |
| TSCA | Yes |
| HS Code | 34029000 |
| Hazard Description | Slightly irritating to eyes and skin; low acute toxicity |
| Handling Advice | Avoid direct eye contact; wear chemical gloves and splash goggles; do not inhale aerosols |
| Storage Requirement | Keep sealed, cool and shaded; prevent freezing and high temperature; keep away from strong oxidants |
This compound is widely used in shampoo, body wash, facial cleanser, hand soap, baby care products, dishwashing liquid and mild detergent formulations. It boosts foam volume and improves foam texture, reduces the irritation of sodium lauryl sulfate and other anionic surfactants. It also works as wetting agent, antistatic agent and viscosity modifier in textile softening and industrial cleaning fields. Thanks to its excellent mildness and compounding performance, it is one of the most mainstream amphoteric surfactants in the personal care industry.






